The following information is exclusively reserved for physicians practicing in Austria, the Netherlands, Spain, and Switzerland where the Zio™ monitor ECG monitoring service is currently authorised and made available for use in accordance with local regulatory requirements.

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The value of the Zio™ service has been demonstrated in over 135 original scientific research manuscripts.1

Publications

Reynolds et al, American Heart Journal, 2023

Comparative Effectiveness and Healthcare Utilization for Ambulatory Cardiac Monitoring Strategies in Medicare Beneficiaries.
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Moss et al, Heart Rhythm, 2023

Simultaneous comparison of patch versus multi-electrode cardiac monitoring for the detection of arrhythmias: The COMPARE study.
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Savur et al, IEEE J Biomed Heal Inform, 2023

Monitoring Pulse Rate in the Background Using Front Facing Cameras of Mobile Devices.
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Gadaleta et al, NPJ Digit Med. 2023

Prediction of atrial fibrillation from at-home single-lead ECG signals without arrhythmias.
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Raghunath et al, J Electrocardiol., 2023

An ECG-based machine learning model for predicting new-onset atrial fibrillation is superior to age and clinical features in identifying patients at high stroke risk.
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Chaitoff et al, J Gen Intern Med., 2023

Patient-Centered Outcomes in Clinical Trials of Wearable Devices for Atrial Fibrillation.
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Irie et al, Int Hear J., 2023

The Relationship between Holter Electrocardiography and Atrial Fibrillation Diagnosis Using Real-World Data in Japan: A Claims-Based Retrospective Study.
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Hong et al, Cambridge University Press, 2023

Cardiac arrhythmias in postural tachycardia syndrome and orthostatic intolerance.
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Etzkorn et al, Stat Biosci., 2023

Classification of Free-Living Body Posture with ECG Patch Accelerometers: Application to the Multicenter AIDS Cohort Study.
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Mustapha et al, JACC: Advances, 2023

Association Between Left Ventricular Scar and Ventricular Ectopy in People Living With and Without HIV.
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Yang et al, JACC: Heart Failure, 2023

Prevalence of Subclinical Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction.
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Yoshida et al, J Am Heart Assoc, 2023

Subclinical Left Ventricular Dysfunction and Ventricular Arrhythmias in Older Adults With Normal Ejection Fraction.
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Poh et al, JAHA, 2023

Validation of a Deep Learning Algorithm for Continuous, Real‐Time Detection of Atrial Fibrillation Using a Wrist‐Worn Device in an Ambulatory Environment.
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Goergen et al, Heart Rhythm, 2023

A Comparison of Data Quality and Monitoring Completion Rates Between Clinic and Self-Applied ECG Patches.
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Marcus et al, New Engl J Med, 2023

Acute Effects of Coffee Consumption on Health among Ambulatory Adults.
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Austin et al, J Am Heart Assoc, 2022

Left Atrial Function and Arrhythmias in Relation to Small Vessel Disease on Brain MRI: The Multi-Ethnic Study of Atherosclerosis.
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Gubitosi-Klug et al, Diabetes Care, 2022

Continuous Glucose Monitoring in Adults With Type 1 Diabetes With 35 Years Duration From the DCCT/EDIC Study.
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Chen et al, JAMA Health Forum., 2022

Cost-effectiveness of Screening for Atrial Fibrillation Using Wearable Devices.
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Gillett et al, Cannabis Cannabinoid Res., 2022

Arrhythmic Effects of Cannabis in Ischemic Heart Disease.
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Reynbakh et al, Am Heart J Plus, 2022

Arrhythmia patterns during and after hospitalization for COVID-19 infection detected via patch-based mobile cardiac telemetry.
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Pothineni et al, J Stroke Cerebrovasc Dis, 2022

Continuous cardiac rhythm monitoring post-stroke: A feasibility study in REGARDS.
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Harding et al, American Journal of Cardiology, 2022

Self-reported marijuana use and cardiac arrhythmias (from the Multiethnic Study of Atherosclerosis).
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Etzkorn et al, AIDS, 2022

Patterns of objectively measured physical activity differ between men living with and without HIV.
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Huber et al, J Am Heart Assoc, 2022

Left Atrial Strain and the Risk of Atrial Arrhythmias From Extended Ambulatory Cardiac Monitoring: MESA.
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Tarakji et al, Heart Rhythm, 2022

Bradyarrhythmias detected by extended rhythm recording in patients undergoing transcatheter aortic valve replacement (Brady-TAVR Study).
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Pang et al, Epilepsy Behav., 2022

Epileptic seizures and Epilepsy Monitoring Unit admission disclose latent cardiac electrical instability.
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Okoh et al, Catheterization & Cardiovascular Interventions, 2022

Utilizing ambulatory electrocardiogram monitoring to reduce conduction related death after transcatheter aortic valve replacement.
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Dewland et al, Open Heart, 2022

Prospective arrhythmia surveillance after a COVID-19 diagnosis.
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Lang et al, Future Health J., 2022

Process and Systems: Improving stroke pathways using an adhesive ambulatory ECG patch: reducing time for patients to ECGs and subsequent results.
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Johansen et al, J Alzheimers Dis, 2022

Associations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study.
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McCarthy et al, J Thorac Cardiovasc Surg., 2022

Three-year outcomes of the postapproval study of the AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation Trial.
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Ma et al, American Journal of Cardiology, 2022

Life’s Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis).
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Gupta et al., The American Journal of Cardiology, 2021

Diagnostic Yield, Outcomes, and Resource Utilization With Different Ambulatory Electrocardiographic Monitoring Strategies.
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Kim et al, J Am Soc Nephrol., 2021

Two-Week Burden of Arrhythmias across CKD Severity in a Large Community-Based Cohort: The ARIC Study.
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Norby et al, Neurology., 2021

Association of Ventricular Arrhythmias With Dementia: The Atherosclerosis Risk in Communities (ARIC) Study.
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Muntané-Carol et al, JACC Cardiovasc Interv., 2021

Ambulatory Electrocardiographic Monitoring Following Minimalist Transcatheter Aortic Valve Replacement.
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McIntyre et al, Crit Care Explorations., 2021

High Sensitivity Estimate of the Incidence of New-Onset Atrial Fibrillation in Critically Ill Patients.
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Krishnappa et al, Int J Cardiol., 2021

Life's Simply 7 cardiovascular health score and premature atrial contractions: The atherosclerosis risk in communities (ARIC) study.
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Assis et al, J Cardiovasc Electrophysiol., 2021

Efficacy of catheter ablation for premature ventricular contractions in arrhythmogenic right ventricular cardiomyopathy.
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Garg et al., The American Journal of Cardiology, 2021

Association of Longitudinal Changes in Cardiac Biomarkers With Atrial and Ventricular Arrhythmias (from the Atherosclerosis Risk in Communities [ARIC] Study).
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Mannina et al, International Journal of Cardiology., 2021

Frequency of cardiac arrhythmias in older adults: Findings from the Subclinical Atrial Fibrillation and Risk of Ischemic Stroke (SAFARIS) study.
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Gladstone et al., JAMA Cardiology, 2021

Screening for Atrial Fibrillation in the Older Population – A Randomized Clinical Trial.
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Feinstein et al, AIDS [Internet]., 2021

Ventricular ectopy and arrhythmia by HIV serostatus, viremia, and CD4+ cell count.
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Nawab et al, Clin Kidney J., 2021

Accelerometer-measured physical activity and functional behaviours amoung people on dialysis.
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Wang et al, J Am Heart Assoc., 2021

Differences in Left Atrial Size and Function and Supraventricular Ectopy Between Black and White Participants in the ARIC Study.
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Cho et al, PLoS One., 2021

Delayed repolarization and ventricular tachycardia in patients with heart failure and preserved ejection fraction.
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Marcus et al, Ann Intern Med., 2021

Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events.
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Steinhubl et al, PLoS One., 2021

Three year clinical outcomes in a nationwide, observational, siteless clinical trial of atrial fibrillation screening -mHealth Screening to Prevent Strokes (mSToPS).
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Rooney et al, Mayo Clin Proc., 2021

Frequent Premature Atrial Contractions Are Associated With Poorer Cognitive Function in the Atherosclerosis Risk in Communities (ARIC) Study.
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Osuji et al, Medicine (Baltimore)., 2021

Association between human immunodeficiency virus serostatus and the prevalence of atrial fibrillation.
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Brunetti et al, Pacing Clin Electrophysiol., 2021

New-onset atrial fibrillation in intensive care: epidemiology and outcomes.
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Tarakji et al., Heart Rhythm Journal, 2021

Bradyarrhythmias Detected by Extended Rhythm Recording in Patients Undergoing Transcatheter Aortic Valve Replacement (Brady-TAVR Study).
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D’Souza et al, Am J Epidemiol., 2021

Characteristics of the MACS/WIHS Combined Cohort Study: Opportunities for Research on Aging With HIV in the Longest US Observational Study of HIV.
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Carruth et al, Circ Genom Precis Med., 2021

Clinical Findings and Diagnositc Yield of Arrhythmogenic Cardiomyopathy Through Genomic Screening of Pathogenic or Likely Pathogenic Desmosome Gene Variants.
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Alonso et al, Nutr Metab Cardiovasc Dis, 2020

Circulating electrolytes and the prevalence of atrial fibrillation and supraventricular ectopy: The Atherosclerosis Risk in Communities (ARIC) study.
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DeLurgio et al, Circ Arrhythm Electrophysiol., 2020

Hybrid Convergent Procedure for the Treatment of Persistent and Long-Standing Persistent Atrial Fibrillation: Results of CONVERGE Clinical Trial.
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Full et al, Sleep Breath, 2020

Association between excessive daytime sleepiness and measures of supraventricular arrhythmia burden: evidence from Atherosclerosis Risk in Communities (ARIC) study.
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Harding et al, Pharmacoepidemiol Drug Saf, 2020

Opiod, gabapentinoid, and nonsteroidal anti-inflammatory medication use and the risks of atrial fibrillation and supraventricular ectopy in the Multi-Ethnic Study of Atherosclerosis.
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Braunstein et al, J Cardiovasc Electrophysiol., 2020

Inpatient cardiac monitoring using a patch-based mobile cardiac telemetry system during the COVID-19 pandemic.
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Heo et al., Cardiovasc Diabetol, 2020

Chronic kidney disease and undiagnozed atrial fibrillation in individuals with diabetes.
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Heravi et al., Circulation, 2020

HIV Infection is Associated With Variability in Ventricular Repolarization.
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Wang et al., Am J Cardiol., 2020

Association of Life's Simple 7 with Atrial Fibrillation Burden (From the Atherosclerosis Risk in Communities Study).
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Gunasekaran et al., Pacing Clin Electrophysiol., 2020

Left ventricular extracellular volume expansion does not predict recurrence of atrial fibrillation following catheter ablation.
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Khan et al., Front Neurol., 2020

Fast-Track Long Term Continuous Heart Monitoring in a Stroke Clinic: A Feasibility Study.
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Quer et al., Europace., 2020

Screening for atrial fibrillation: predicted sensitivity of short, intermittent electrocardiogram recordings in an asymptomatic at-risk population.
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Waalen et al., Heart Rhythm O2, 2020

Healthcare Resource Utilization Following ECG Sensor Patch Screening for Atrial Fibrillation.
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Rooney et al., J Electrocardiol., 2020

Serum magnesium and burden of atrial and ventricular arrhythmias: The Atherosclerosis Risk in Communities (ARIC) Study.
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Kim et al., J Electrocardiol., 2020

Diurnal circadian variations in paroxysmal atrial fibrillation: The atherosclerosis risk in communities (ARIC) study.
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Heckbert et al, Circ Arrhythmia Electrophysiol., 2020

Differences by Race/Ethnicity in the Prevalence of Clinically Detected and Monitor-Detected Atrial Fibrillation.
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Eysenck et al., J Interv Card Electrophysiol., 2019

A randomized trial evaluating the accuracy of AF detection by four external ambulatory ECG monitors compared to permament pacemaker AF detection.
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Hannun et al., Nature Medicine, 2019

Cardiologist-Level Arrhythmia Detection and Classification in Ambulatory Electrocardiograms Using a Deep Neural Network.
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Eysenck et al., Journal of Interventional Cardiac Electrophysiology, 2019

A Randomized Trial Evaluating the Accuracy of AF Detection by Four External Ambulatory ECG Monitors Compared to Permanent Pacemaker AF Detection.
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Kaura et al., European Journal of Medical Research, 2019

Early Prolonged Ambulatory Cardiac Monitoring in Stroke (EPACS): An Open-Label Randomised Controlled Trial.
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Yenikomshian et al., Current Medical Research and Opinion, 2019

Cardiac Arrhythmia Detection Outcomes Among Patients Monitored With the Zio Patch System: A Systematic Literature Review.
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Rooney et al., Circ Arrhythmia Electrophysiol., 2019

Prevalence and Characteristics of Subclinical Atrial Fibrillation in a Community-Dwelling Elderly Population: The ARIC Study.
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McNamara et al., Circulation. 2019

Left Atrial Electromechanical Remodeling Following 2 Years of High-Intensity Exercise Training in Sedentary Middle-Aged Adults.
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Baca-Motes et al., Contemp Clin Trials Commun., 2019

Digital recruitment and enrollment in a remote nationwide trial of screening for undiagnosed atrial fibrillation: Lessons from the randomized, controlled mSToPS trial.
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Pang et al., Neurology, 2019

Cardiac electrical instability in newly diagnosed/chronic epilepsy tracked by Holter and ECG patch.
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Schultz et al., Congenit Heart Dis., 2019

Extended cardiac ambulatory rhythm monitoring in adults with congenital heart disease: Arrhythmia detection and impact of extended monitoring.
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Donnellan et al., Circ Arrhythm Electrophysiol., 2019

Outcomes of Atrial Fibrillation Ablation in Morbidly Obese Patients Following Bariatric Surgery Compared With a Nonobese Cohort.
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Gunda et al., J Cardiovasc Electrophysiol. 2019

Consequences of chronic frequent premature atrial contractions: Association with cardiac arrhythmias and cardiac structural changes.
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Wadia et al., Congenit Heart Dis., 2019

Postoperative and short-term atrial tachyarrhythmia burdens after transcatheter vs surgical pulmonary valve replacement among congenital heart disease patients.
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Mullis et al., Heart Rhythm, 2019

Fluctuations in Premature Ventricular Contraction Burden Can Affect Medical Assessment and Management.
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Rogovoy et al., J Am Heart Assoc., 2019

Hemodialysis Procedure-Associated Autonomic Imbalance and Cardiac Arrhythmias: Insights From Continuous 14-Day ECG Monitoring.
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Taylor et al., Neurology., 2019

Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial.
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Wineinger et al., Heart Rhythm Journal, 2019

Identification of Paroxysmal Atrial Fibrillation Subtypes in Over 13,000 Individuals.
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Go et al., JAMA Cardiology, 2018

Association of Burden of Atrial Fibrillation With Risk of Ischemic Stroke in Adults With Paroxysmal Atrial Fibrillation: The KP-RHYTHM Study.
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Opondo et al., Circ Arrhythm Electrophysiol., 2018

Does High-Intensity Endurance Training Increase the Risk of Atrial Fibrillation.
Zio by iRhythm is dedicated to providing clinicians with peer-reviewed scientific evidence. With over 100 publications, Zio is the industry leader that first identified and met the need for long-term continuous monitoring.
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Heckbert et al., Journal of Electrocardiology, 2018

Yield and Consistency of Arrhythmia Detection With Patch Electrocardiographic Monitoring: The Multi-Ethnic Study of Atherosclerosis.
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Reed et al., Emergency Care Journal, 2018

Brain Natriuretic Peptide and High-Sensitivity Troponin at 3 Hours Post Emergency Department Attendance With Unexplained Syncope Predict 90 Day Outcome.
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Lutsey et al., Nutrients, 2018

A Pilot Randomized Trial of Oral Magnesium Supplementation on Supraventricular Arrhythmias.
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Steinhubl et al., JAMA, 2018

Effect of a Home-Based Wearable Continuous ECG Monitoring Patch on Detection of Undiagnosed Atrial Fibrillation: The mSToPS Randomized Clinical Trial.
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Wadia et al., Heart., 2018

Ventricular arrhythmia burden after transcatheter versus surgical pulmonary valve replacement.
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Reed et al., Emergency Medicine Journal, 2018

Diagnostic Yield of an Ambulatory Patch Monitor in Patients With Unexplained Syncope After Initial Evaluation in the Emergency Department: The PATCH-ED Study.
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Zhang et al., Pacing Clin Electrophysiol., 2018

Feasibility of using a leadless patch monitor in community cohort studies: The Multi-ethnic Study of Atherosclerosis.
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Muse et al., PLOS Medicine, 2018

Validation of a Genetic Risk Score for Atrial Fibrillation: A Prospective Multicenter Cohort Study.
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  1. Data on file. iRhythm Technologies, 2026.

 

The Zio™ service is a long-term continuous ambulatory cardiac monitoring service. It consists of the Zio™ monitor that collects beat-to-beat ECG data and can be worn for up to 14 days; the Zio™ ECG Utilization Service (ZEUS) System deep learned algorithm, which detects arrhythmias. The data is reviewed and curated by a team of Qualified ECG Specialists (QES) to provide the final patient report.

For indications for use, warnings & contraindications, visit here.

iRhythm, Zio, Zio monitor and ZioSuite are trademarks of iRhythm Technologies, Inc. ©2024 All rights reserved.

Zio™ monitor and ZEUS are CE-marked (CE2797).

Zio monitor, ZEUS and Zio service are currently available in Austria, Netherlands, Spain & Switzerland.

For further regulatory information visit here.

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