AVALON: Another large real-world study comparing ambulatory cardiac monitoring services

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Clarity by Design

The iRhythm® cardiac monitoring service combines thoughtfully engineered devices, intelligent algorithms, and expert clinical review.

From seamless patient wear to physician-ready reports, every element works together to deliver precise answers when they matter most.

Female physician

Learn how our end-to-end cardiac monitoring service can help you create a better experience for your patients and achieve your program goals. 

Patient wearing Zio monitor pouring a smoothie
Find support throughout your iRhythm cardiac monitoring experience with answers to commonly asked questions.

Clarity That Drives Confidence

Through advanced monitoring technology, intelligent algorithms, and expert clinical review, iRhythm delivers meaningful, actionable data — helping clinicians diagnose with greater confidence from the start.1

Improved wear experience

Zio ECG monitors are designed to be comfortable2-3 and easy to wear3-4 for better patient satisfaction and compliance2-3

Patient wearing Zio monitor

Outstanding patient compliance

Near-perfect patient compliance5 generates high-quality, actionable data1

Remarkable clinical outcomes

Compared to other monitoring services, including long-term continuous monitors (LTCMs), the iRhythm LTCM service is a continuous, uninterrupted10 cardiac monitor associated with:

 

Highest diagnostic yield of specified arrhythmias6-10

Lowest likelihood of retesting6-10

More than a monitor

The iRhythm monitoring service delivers clarity at every step — from the moment a Zio® ECG monitor is prescribed and worn, through advanced AI-assisted analysis and expert review, to physician-ready, clinically actionable reports. With intuitive tools like the ZioSuite® portal, seamless EHR integration, and patient-centric support via the MyZio® app, the iRhythm monitoring service helps simplify workflows and bring meaningful insight to your practice.

iRhythm technology on laptop and cell phone
Allows providers to interpret reports, manage patients, and more — from the computer or on the go with the provider mobile app.11
Simplifies data collection and entry, enhances interdisciplinary access, and boosts workflow efficiency.
Equips physicians with a full wear-time analysis, using FDA-cleared advanced AI technology and verified by Qualified Cardiac Technicians (QCTs).12-15
Supports patients throughout their monitoring journey with digital symptom logging, educational content, and reminders.
User researching iRhythm on computer

Incredible 99% physician agreement with end-of-wear reports

The iRhythm monitoring service combines the first FDA-cleared, deep-learned algorithm verified by QCTs12-15 to generate reports with 99% physician agreement,16 which can lead to an accurate and more timely diagnosis.1,6-10

Over 12 million patients analyzed17

Over 2 billion hours of curated heartbeat data4

Comprehensive reports verified by QCTs12-15

Keep reading

Clinical Article
Russo P, Coetzer H, Hendrickson EM, Boyle K, Wright B., Am J Manag Care. 2025
Assessment of Variation in Ambulatory Cardiac Monitoring (AVALON) Study
A retrospective study of analyzing commercially insured patient populations, examined how monitoring strategy influenced arrhythmia diagnosis, clinical outcomes, and healthcare resource utilization.
Read more
Clinical Article
Reynolds et al, American Heart Journal, 2023.
Comparative Effectiveness of ACM Strategies (CAMELOT Study)
A retrospective study of variations in ACM strategies, clinical outcomes and health care costs in diagnostic-naïve patients
Read more
Clinical Article
Barrett et al., American Journal of Medicine, 2014.
Comparison of 24-Hour Holter Monitoring Versus 14-Days
A prospective study comparing the detection of arrhythmia events over total wear time with the Zio device to Holter monitoring
Read more
  1. Data on file. iRhythm Technologies, 2023.
  2. Zio Monitor Instructions for Use. iRhythm Technologies.
  3. Battisti et al. Abstract 4141717: Feasibility of point-of-wear patient satisfaction surveys to validate patient-centered product enhancements: results from over 300,000 patients for long-term ambulatory cardiac monitoring. Circulation. 2024;150:A4141717. doi:10.1161/circ.150.suppl_1.4141717. https://www.ahajournals.org/doi/abs/10.1161/circ.150.suppl_1.4141717
  4. Data on file. iRhythm Technologies, 2024
  5. Data on file. iRhythm Technologies, 2022.
  6. Reynolds et al. Comparative effectiveness and healthcare utilization for ambulatory cardiac monitoring strategies in Medicare beneficiaries. Am Heart J. 2024;269:2534. https://doi.org/10.1016/j.ahj.2023.12.002
  7. A specified arrhythmia refers to an arrhythmia encounter diagnosis as per Hierarchical Condition Categories (HCC) 96.
  8. The study is based on the previous generation Zio XT device data. The devices used in the Zio LTCM monitoring service are deemed substantially equivalent. Additional data on file.
  9. Zio LTCM service refers to Zio XT and Zio monitor service. 
  10. The Zio service facilitates a diagnosis as determined by a physician.
  11. ZioSuite Clinical Reference Manual. iRhythm Technologies.
  12. Data on file. iRhythm Technologies, 2020.
  13. Hannun et al. Cardiologist-level arrhythmia detection and classification in ambulatory electrocardiograms using a deep neural network. Nat Med. 2019;25:65-69. https://doi.org/10.1038/s41591-018-0268-3
  14. Deep learned algorithm is only available in the United States, the European Union, Switzerland, the United Kingdom, and Japan. 
  15. FDA 510K clearance, CE mark, UKCA mark, and PMDA-approval.
  16. 99% of physicians agree with the comprehensive end-of-wear report. Based on a review of all online Zio XT, Zio monitor, and Zio AT end-of-wear reports. Data on file. iRhythm Technologies, 2023.
  17. Data on file. iRhythm Technologies. 2026.

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